| Game | Date | Home Team | Away Team | Form | League Position | |||||
| 28 | 01/04/2012 | L | Perth Glory | 3 | Melbourne Heart | 0 | ||||
| 27 | 23/03/2012 | D | Adelaide United | 1 | Melbourne Heart | 1 |  | (H) | 6th |  |
| 26 | 17/03/2012 | D | Melbourne Heart | 2 | Sydney FC | 2 | | (H) | 5th | |
| 25 | 10/03/2012 | D | Melbourne Heart | 1 | Wellington Phoenix | 1 | | (H) | 5th | |
| 24 | 02/03/2012 | D | Brisbane Roar | 1 | Melbourne Heart | 1 | | (H) | 5th | |
| 23 | 26/02/2012 | W | Melbourne Heart | 1 | Central Coast Mariners | 0 | | (H) | 5th | |
| 22 | 17/02/2012 | W | Melbourne Heart | 1 | Gold Coast United | 0 | | (H) | 5th | |
| 21 | 11/02/2012 | L | Newcastle Jets | 3 | Melbourne Heart | 0 | | (H) | 6th | |
| 20 | 04/02/2012 | D | Melbourne Heart | 0 | Melbourne Victory | 0 | | (H) | 5th | |
| 19 | 29/01/2012 | L | Wellington Phoenix | 3 | Melbourne Heart | 1 | | (H) | 5th | |
| 18 | 21/01/2012 | D | Melbourne Heart | 1 | Brisbane Roar | 1 | | (H) | 4th | |
| 17 | 18/01/2012 | L | Melbourne Heart | 0 | Central Coast Mariners | 1 | | (H) | 3rd | |
| 16 | 15/01/2012 | L | Melbourne Heart | 1 | Perth Glory | 2 | | (H) | 3rd | |
| 15 | 08/01/2012 | D | Gold Coast United | 1 | Melbourne Heart | 1 | | (H) | 3rd | |
| 14 | 04/01/2012 | L | Melbourne Heart | 1 | Adelaide United | 3 | | (H) | 3rd | |
| 13 | 29/12/2011 | W | Sydney FC | 0 | Melbourne Heart | 4 | | (H) | 2nd | |
| 12 | 23/12/2011 | W | Melbourne Heart | 3 | Melbourne Victory | 2 | | (H) | 2nd | |
| 11 | 17/12/2011 | W | Perth Glory | 1 | Melbourne Heart | 2 | | (H) | 3rd | |
| 10 | 09/12/2011 | W | Brisbane Roar | 1 | Melbourne Heart | 2 | | (H) | 3rd | |
| 9 | 04/12/2011 | W | Melbourne Heart | 1 | Wellington Phoenix | 0 | | (H) | 6th | |
| 8 | 26/11/2011 | L | Central Coast Mariners | 3 | Melbourne Heart | 1 |  | (H) | 7th | |
| 7 | 18/11/2011 | W | Gold Coast United | 1 | Melbourne Heart | 2 | | (H) | 5th | |
| 6 | 12/11/2011 | W | Melbourne Heart | 3 | Newcastle Jets | 0 | | (H) | 8th | |
| 5 | 04/11/2011 | D | Adelaide United | 1 | Melbourne Heart | 1 | | (H) | 10th | |
| 4 | 29/10/2011 | D | Melbourne Heart | 1 | Sydney FC | 1 | | (H) | 10th | |
| 3 | 22/10/2011 | D | Melbourne Victory | 0 | Melbourne Heart | 0 | | (H) | 9th | |
| 2 | 16/10/2011 | L | Melbourne Heart | 1 | Perth Glory | 2 | | (H) | 10th | |
| 1 | 08/10/2011 | L | Newcastle Jets | 3 | Melbourne Heart | 2 | | (H) | 10th | |
