| Game | Date | Home Team | Away Team | Form | League Position | |||||
| 34 | 29/04/2012 | D | Sint-Niklaas | 0 | Eupen | 0 | Current Table | |||
| 33 | 20/04/2012 | D | Waasland | 1 | Sint-Niklaas | 1 |  | (H) | 15th |  |
| 32 | 14/04/2012 | L | KVSK United | 2 | Sint-Niklaas | 0 | | (H) | 16th | |
| 31 | 11/04/2012 | D | Boussu Dour Borinage | 1 | Sint-Niklaas | 1 | | (H) | 15th | |
| 30 | 06/04/2012 | D | Sint-Niklaas | 1 | Oostende | 1 | | (H) | 15th | |
| 29 | 31/03/2012 | D | Sint-Niklaas | 1 | Roeselare | 1 |  | (H) | 15th | |
| 28 | 25/03/2012 | D | Sint-Niklaas | 1 | Dender | 1 | | (H) | 14th | |
| 27 | 17/03/2012 | W | Standaard Wetteren | 1 | Sint-Niklaas | 2 | | (H) | 14th | |
| 26 | 11/03/2012 | W | Eendracht Aalst | 1 | Sint-Niklaas | 3 | | (H) | 15th | |
| 25 | 04/03/2012 | L | Sint-Niklaas | 0 | Tienen | 1 | | (H) | 16th | |
| 24 | 26/02/2012 | L | Charleroi | 3 | Sint-Niklaas | 1 | | (H) | 15th | |
| 23 | 18/02/2012 | W | Sint-Niklaas | 3 | Tubize | 0 | | (H) | 15th | |
| 22 | 29/01/2012 | D | FC Brussels | 2 | Sint-Niklaas | 2 | | (H) | 15th | |
| 21 | 22/01/2012 | W | Sint-Niklaas | 2 | Antwerp | 1 | | (H) | 15th | |
| 20 | 15/01/2012 | D | White Star Woluwe | 2 | Sint-Niklaas | 2 | | (H) | 17th | |
| 19 | 08/01/2012 | W | Sint-Niklaas | 1 | Vise | 0 | | (H) | 17th | |
| 18 | 18/12/2011 | L | Heist | 4 | Sint-Niklaas | 3 | | (H) | 17th | |
| 17 | 10/12/2011 | L | Eupen | 2 | Sint-Niklaas | 1 | | (H) | 16th | |
| 16 | 04/12/2011 | L | Sint-Niklaas | 1 | Waasland | 2 | | (H) | 16th | |
| 15 | 27/11/2011 | L | Sint-Niklaas | 0 | KVSK United | 3 | | (H) | 16th | |
| 14 | 20/11/2011 | L | Oostende | 4 | Sint-Niklaas | 1 | | |||
| 13 | 13/11/2011 | L | Sint-Niklaas | 0 | Standaard Wetteren | 1 | | (H) | 16th | |
| 12 | 05/11/2011 | L | Roeselare | 2 | Sint-Niklaas | 0 | | (H) | 16th | |
| 11 | 30/10/2011 | L | Sint-Niklaas | 1 | Eendracht Aalst | 2 | | (H) | 15th | |
| 10 | 23/10/2011 | W | Tienen | 2 | Sint-Niklaas | 4 | | (H) | 13th | |
| 9 | 16/10/2011 | L | Sint-Niklaas | 1 | Charleroi | 2 | | (H) | 15th | |
| 8 | 09/10/2011 | L | Sint-Niklaas | 0 | Boussu Dour Borinage | 1 | | (H) | 13th | |
| 7 | 01/10/2011 | D | Tubize | 1 | Sint-Niklaas | 1 | | (H) | 11th | |
| 6 | 25/09/2011 | W | Sint-Niklaas | 1 | FC Brussels | 0 | | (H) | 10th | |
| 5 | 17/09/2011 | L | Dender | 3 | Sint-Niklaas | 1 | | (H) | 14th | |
| 4 | 10/09/2011 | L | Antwerp | 2 | Sint-Niklaas | 0 | | (H) | 10th | |
| 3 | 04/09/2011 | W | Sint-Niklaas | 3 | White Star Woluwe | 2 | | (H) | 8th | |
| 2 | 24/08/2011 | L | Vise | 2 | Sint-Niklaas | 1 | | (H) | 14th | |
| 1 | 17/08/2011 | D | Sint-Niklaas | 1 | Heist | 1 | | (H) | 10th | |
