| Game | Date | Home Team | Away Team | Form | League Position | |||||
| 30 | 21/03/2012 | L | KV Mechelen | 1 | Standard Liege | 2 | Current Table | |||
| 29 | 18/03/2012 | L | Zulte Waregem | 2 | KV Mechelen | 0 |  | (H) | 9th |  |
| 28 | 03/03/2012 | L | KV Mechelen | 0 | Gent | 2 | | (H) | 9th | |
| 27 | 25/02/2012 | W | Westerlo | 1 | KV Mechelen | 3 | | (H) | 9th | |
| 26 | 18/02/2012 | W | KV Mechelen | 2 | Germinal Beerschot | 1 | | (H) | 9th | |
| 25 | 11/02/2012 | L | Cercle Brugge | 1 | KV Mechelen | 0 | | (H) | 10th | |
| 24 | 04/02/2012 | D | KV Mechelen | 0 | Kortrijk | 0 | | (H) | 8th | |
| 23 | 28/01/2012 | L | Lokeren | 3 | KV Mechelen | 2 | | (H) | 8th | |
| 22 | 25/01/2012 | W | KV Mechelen | 3 | Genk | 2 | | (H) | 8th | |
| 21 | 21/01/2012 | W | Club Brugge | 0 | KV Mechelen | 1 | | (H) | 10th | |
| 20 | 14/01/2012 | W | KV Mechelen | 4 | Mons | 1 | | (H) | 10th | |
| 19 | 26/12/2011 | D | KV Mechelen | 2 | Oud Heverlee | 2 | | (H) | 10th | |
| 18 | 17/12/2011 | D | St Truiden | 0 | KV Mechelen | 0 | | (H) | 10th | |
| 17 | 09/12/2011 | W | KV Mechelen | 2 | Anderlecht | 1 | | (H) | 11th | |
| 16 | 03/12/2011 | D | Lierse | 2 | KV Mechelen | 2 | | (H) | 11th | |
| 15 | 25/11/2011 | L | Standard Liege | 3 | KV Mechelen | 2 | | (H) | 11th | |
| 14 | 19/11/2011 | D | KV Mechelen | 1 | Zulte Waregem | 1 | | (H) | 11th | |
| 13 | 04/11/2011 | L | Gent | 6 | KV Mechelen | 2 | | (H) | 12th | |
| 12 | 29/10/2011 | W | KV Mechelen | 1 | Westerlo | 0 | | (H) | 11th | |
| 11 | 22/10/2011 | D | Germinal Beerschot | 2 | KV Mechelen | 2 | | (H) | 11th | |
| 10 | 15/10/2011 | L | KV Mechelen | 1 | Cercle Brugge | 2 | | (H) | 13th | |
| 9 | 01/10/2011 | L | Kortrijk | 1 | KV Mechelen | 0 | | (H) | 12th | |
| 8 | 24/09/2011 | L | KV Mechelen | 0 | Lokeren | 2 | | (H) | 10th | |
| 7 | 17/09/2011 | L | Mons | 5 | KV Mechelen | 1 | | (H) | 9th | |
| 6 | 11/09/2011 | L | KV Mechelen | 1 | Club Brugge | 2 |  | (H) | 6th | |
| 5 | 27/08/2011 | D | Genk | 0 | KV Mechelen | 0 | | (H) | 3rd | |
| 4 | 20/08/2011 | W | Oud Heverlee | 1 | KV Mechelen | 2 | | (H) | 1st | |
| 3 | 14/08/2011 | W | KV Mechelen | 2 | Lierse | 1 | | (H) | 3rd | |
| 2 | 05/08/2011 | L | Anderlecht | 3 | KV Mechelen | 1 | | (H) | 8th | |
| 1 | 30/07/2011 | W | KV Mechelen | 2 | St Truiden | 1 | | (H) | 3rd | |
