| Game | Date | Home Team | Away Team | Form | League Position | |||||
| 41 | 20/05/2012 | D | Grosseto | 1 | Empoli | 1 | Current Table | |||
| 40 | 12/05/2012 | D | Empoli | 1 | Vicenza | 1 |  | (H) | 17th |  |
| 39 | 08/05/2012 | W | Albinoleffe | 0 | Empoli | 2 | | (H) | 17th | |
| 38 | 05/05/2012 | D | Ascoli | 1 | Empoli | 1 | | (H) | 17th | |
| 37 | 01/05/2012 | W | Empoli | 2 | Gubbio | 1 | | (H) | 18th | |
| 36 | 27/04/2012 | D | Hellas Verona | 0 | Empoli | 0 | | (H) | 18th | |
| 35 | 21/04/2012 | L | Empoli | 1 | Modena | 3 | | (H) | 18th | |
| 34 | 06/04/2012 | L | Nocerina | 2 | Empoli | 1 | | (H) | 18th | |
| 33 | 31/03/2012 | W | Empoli | 1 | Torino | 0 | | (H) | 18th | |
| 32 | 23/03/2012 | L | Sassuolo | 1 | Empoli | 0 | | (H) | 18th | |
| 31 | 17/03/2012 | W | Empoli | 1 | Bari | 0 | | (H) | 18th | |
| 30 | 10/03/2012 | W | Varese | 0 | Empoli | 1 | | (H) | 19th | |
| 29 | 06/03/2012 | L | Sampdoria | 1 | Empoli | 0 | | (H) | 20th | |
| 28 | 03/03/2012 | D | Empoli | 1 | Livorno | 1 | | (H) | 20th | |
| 27 | 18/02/2012 | D | Padova | 1 | Empoli | 1 | | (H) | 19th | |
| 26 | 11/02/2012 | L | Reggina | 3 | Empoli | 2 | | (H) | 19th | |
| 25 | 04/02/2012 | D | Empoli | 1 | Crotone | 1 | | (H) | 19th | |
| 24 | 28/01/2012 | L | Empoli | 0 | Brescia | 2 | | (H) | 21st | |
| 23 | 21/01/2012 | L | Empoli | 0 | Pescara | 2 | | (H) | 20th | |
| 22 | 14/01/2012 | L | Juve Stabia | 3 | Empoli | 1 | | (H) | 18th | |
| 21 | 06/01/2012 | L | Cittadella | 2 | Empoli | 1 | | (H) | 16th | |
| 20 | 17/12/2011 | D | Empoli | 2 | Grosseto | 2 | | (H) | 15th | |
| 19 | 10/12/2011 | L | Vicenza | 1 | Empoli | 0 | | (H) | 15th | |
| 18 | 03/12/2011 | W | Empoli | 3 | Ascoli | 2 |  | (H) | 14th | |
| 17 | 27/11/2011 | W | Gubbio | 0 | Empoli | 1 | | (H) | 16th | |
| 16 | 19/11/2011 | L | Empoli | 1 | Hellas Verona | 3 | | (H) | 17th | |
| 15 | 13/11/2011 | W | Modena | 0 | Empoli | 2 | | (H) | 17th | |
| 14 | 05/11/2011 | D | Empoli | 0 | Albinoleffe | 0 | | (H) | 21st | |
| 13 | 01/11/2011 | W | Empoli | 2 | Nocerina | 0 | | (H) | 20th | |
| 12 | 29/10/2011 | L | Torino | 2 | Empoli | 1 | | (H) | 22nd | |
| 11 | 22/10/2011 | D | Empoli | 1 | Sassuolo | 1 | | (H) | 20th | |
| 10 | 15/10/2011 | L | Bari | 1 | Empoli | 0 | | (H) | 19th | |
| 9 | 09/10/2011 | L | Empoli | 1 | Varese | 2 | | (H) | 19th | |
| 8 | 05/10/2011 | D | Livorno | 0 | Empoli | 0 | | (H) | 18th | |
| 7 | 01/10/2011 | L | Empoli | 2 | Padova | 4 | | (H) | 19th | |
| 6 | 26/09/2011 | W | Empoli | 3 | Reggina | 2 | | (H) | 15th | |
| 5 | 17/09/2011 | L | Crotone | 2 | Empoli | 1 | | (H) | 19th | |
| 4 | 12/09/2011 | L | Empoli | 1 | Sampdoria | 3 | | (H) | 16th | |
| 3 | 04/09/2011 | L | Brescia | 2 | Empoli | 1 | | (H) | 16th | |
| 2 | 30/08/2011 | L | Pescara | 3 | Empoli | 2 | | (H) | 12th | |
| 1 | 27/08/2011 | W | Empoli | 2 | Juve Stabia | 1 | | (H) | 6th | |
