| Game | Date | Home Team | Away Team | Form | League Position | |||||
| 34 | 06/05/2012 | W | Excelsior Rotterdam | 1 | PSV | 3 | Current Table | |||
| 33 | 02/05/2012 | W | PSV | 5 | ADO Den Haag | 0 |  | (H) | 3rd | |
| 32 | 29/04/2012 | W | Roda JC | 1 | PSV | 3 | | (H) | 3rd | |
| 31 | 22/04/2012 | W | PSV | 2 | NEC | 1 | | (H) | 5th | |
| 30 | 14/04/2012 | W | PSV | 3 | AZ | 2 | | (H) | 5th | |
| 29 | 11/04/2012 | L | RKC Waalwijk | 2 | PSV | 1 | | (H) | 5th | |
| 28 | 31/03/2012 | W | PSV | 2 | VVV Venlo | 0 |  | (H) | 4th | |
| 27 | 25/03/2012 | L | Ajax | 2 | PSV | 0 | | (H) | 4th | |
| 26 | 18/03/2012 | W | PSV | 5 | Heerenveen | 1 | | (H) | 3rd | |
| 25 | 11/03/2012 | L | NAC | 3 | PSV | 1 | | (H) | 4th | |
| 24 | 04/03/2012 | L | PSV | 2 | FC Twente | 6 | | (H) | 3rd | |
| 23 | 26/02/2012 | W | PSV | 3 | Feyenoord | 2 | | (H) | 1st | |
| 22 | 19/02/2012 | L | FC Groningen | 3 | PSV | 0 | | (H) | 1st | |
| 21 | 12/02/2012 | W | PSV | 4 | De Graafschap | 1 | | (H) | 1st | |
| 20 | 05/02/2012 | D | Heracles | 1 | PSV | 1 | | (H) | 1st | |
| 19 | 27/01/2012 | W | PSV | 3 | Vitesse | 1 | | (H) | 1st | |
| 18 | 22/01/2012 | D | FC Utrecht | 1 | PSV | 1 | | (H) | 2nd | |
| 17 | 18/12/2011 | W | Heerenveen | 1 | PSV | 5 | | (H) | 2nd | |
| 16 | 10/12/2011 | W | PSV | 1 | NAC | 0 | | (H) | 2nd | |
| 15 | 04/12/2011 | L | Feyenoord | 2 | PSV | 0 | | (H) | 2nd | |
| 14 | 26/11/2011 | W | PSV | 6 | FC Groningen | 1 | | (H) | 2nd | |
| 13 | 19/11/2011 | W | De Graafschap | 1 | PSV | 3 | | (H) | 2nd | |
| 12 | 06/11/2011 | W | PSV | 4 | Heracles | 1 | | (H) | 3rd | |
| 11 | 29/10/2011 | D | FC Twente | 2 | PSV | 2 |  | (H) | 2nd | |
| 10 | 23/10/2011 | D | Vitesse | 1 | PSV | 1 | | (H) | 2nd | |
| 9 | 15/10/2011 | W | PSV | 1 | FC Utrecht | 0 | | (H) | 2nd | |
| 8 | 02/10/2011 | W | NEC | 0 | PSV | 2 | | (H) | 2nd | |
| 7 | 24/09/2011 | W | PSV | 7 | Roda JC | 1 | | (H) | 4th | |
| 6 | 18/09/2011 | D | PSV | 2 | Ajax | 2 | | (H) | 5th | |
| 5 | 11/09/2011 | D | VVV Venlo | 3 | PSV | 3 | | (H) | 5th | |
| 4 | 28/08/2011 | W | PSV | 6 | Excelsior Rotterdam | 1 | | (H) | 3rd | |
| 3 | 21/08/2011 | W | ADO Den Haag | 0 | PSV | 3 | | (H) | 6th | |
| 2 | 13/08/2011 | W | PSV | 1 | RKC Waalwijk | 0 | | (H) | 9th | |
| 1 | 07/08/2011 | L | AZ | 3 | PSV | 1 | | (H) | 16th | |
